Biotic⁺
£40
Science deep dive Vitals
Thrive⁺ is a science-led longevity supplement. Powered by 4 high-impact nutrients for cellular energy and vitality. It's individual ingredients is backed by 1,000+ studies, and a clinical trial.
Formulation
NAD⁺ is a molecule found naturally in every cell, helping turn nutrients into cellular energy. Levels naturally decline with age.
Clinically measured:
- Whole-blood NAD⁺ increased by 49% after 30 days of Thrive⁺
Found naturally in your mitochondria, where it helps produce ATP – the usable energy your cells need to function.
Clinically measured:
- Plasma CoQ10 increased by 57% after 30 days of Thrive⁺
A polyphenol that helps support the cellular systems involved in healthy ageing – helping cells better handle everyday wear and tear.
Studied for its role in:
- Complementing healthy ageing
- Supporting long-term cellular resilience
- Maintaining cellular energy pathways
An essential mineral that supports energy production and helps keep the body’s cellular systems working as they should.
Contributes to:
- Normal energy-yielding metabolism
- Cell protection from oxidative stress
- Normal connective tissue health
Science of cellular energy
Inside your cells, mitochondria turn nutrients into ATP – the usable energy your body relies on. NAD⁺ and CoQ10 both play key roles in this process.
Why NAD⁺ matters with age
NAD⁺ occurs naturally throughout the body, but levels decline with age – making NAD⁺ metabolism an important area of healthy ageing research.
Our clinical trials
Cellular energy & wellbeing pilot study
METHODOLOGY
This studied comprised of 18 healthy adults aged 35-65 took Thrive⁺ daily, with NAD⁺, CoQ10 and a range of cardiovascular, physical, blood and mental wellbeing measures assessed at baseline and after 30 days.
The independent study was open-label and single-arm, with no placebo group; each participant was compared with their own baseline.
THE RESULTS
1. NAD⁺ increased by 49%
After 30 days, whole-blood NAD⁺ increased from 14.04 to 20.92 µg/mL – a statistically significant rise in a key molecule involved in cellular energy production.
2. CoQ10 increased by 57%
After 30 days, plasma CoQ10 increased from 5.14 to 8.06 ng/mL – also a statistically significant rise in a key compound involved in mitochondrial energy production.
3. Thrive⁺ wasn’t just increasing NAD⁺ – the body was using it
Researchers also measured 1-Methyl Nicotinamide (MNA), produced when NAD⁺ is metabolised.
MNA increased by 120% over the 30 days which suggests NAD⁺ pathways were actively being used by the body.
4. Significant improvements in mental wellbeing
Two validated clinical questionnaires showed statistically significant improvements in how participants felt.
The GHQ-12, a recognised measure of psychological wellbeing, improved by 10%, including:
- +31% confidence
- +23% improvement in low mood
- +19% concentration
The Profile of Mood States (POMS) also improved significantly, including:
- 32% less confusion
- 17% greater vigour
5. Systolic blood pressure fell by 7.7 mmHg
After 30 days, average systolic blood pressure decreased from 128.9 to 121.2 mmHg.
Systolic blood pressure measures the pressure in your arteries when your heart beats, making it an important marker of cardiovascular health.
3rd party quality control
Tested for optimal safety
What to expect
Thrive⁺ shows measurable cellular changes in 30 days, but it’s designed for long-term use to support cellular energy and vitality.
24 HOURS
Your cells begin producing more NAD⁺ from NR, supporting the cellular processes involved in energy production.
BY DAY 30
After 30 days of Thrive⁺, whole-blood NAD⁺ increased by 49% and CoQ10 by 57% in our pilot study.
BY DAY 45
Clinical research around this point suggests higher NAD⁺ availability may support changes in body composition, including lean muscle.
BY DAY 180
Sustained increases in NAD⁺ may support everyday energy and endurance. In one 2020 study, participants improved their 6-minute walking distance by 17.6 metres.
AFTER 365 DAYS
With continued use, the aim is to consistently support your NAD⁺ pathway and the cellular processes associated with long-term healthy ageing.
Interactions
If you take blood thinners or antiplatelet medication such as warfarin, clopidogrel or aspirin, speak to your doctor or pharmacist before using Thrive⁺, as trans-resveratrol and CoQ10 may affect bleeding or warfarin activity.
Caution is also sensible if you take blood-pressure medication, and high dose zinc supplements can reduce copper absorption.
If you’re pregnant, breastfeeding, taking prescription medication or have a medical condition, check with a healthcare professional before use.
