Biotic⁺
£40
Science deep dive Vitals
Thrive is a UK-first longevity supplement combining 4 high-impact nutrients. Together they’re backed by 1,000+ studies, and the formula was third-party tested in a human clinical trial.
Formulation
NAD⁺ is a molecule found naturally in every cell, helping turn nutrients into cellular energy. Levels naturally decline with age.
Clinically measured:
- Whole-blood NAD⁺ increased by 49% after 30 days of Thrive⁺
Found naturally in your mitochondria, where it helps produce ATP – the usable energy your cells need to function.
Clinically measured:
- Plasma CoQ10 increased by 57% after 30 days of Thrive⁺
A polyphenol that helps support the cellular systems involved in healthy ageing – helping cells better handle everyday wear and tear.
Studied for its role in:
- Complementing healthy ageing
- Supporting long-term cellular resilience
- Maintaining cellular energy pathways
An essential mineral that supports energy production and helps keep the body’s cellular systems working as they should.
Contributes to:
- Normal energy-yielding metabolism
- Cell protection from oxidative stress
- Normal connective tissue health
Science of cellular energy
Inside your cells, mitochondria turn nutrients into ATP – the usable energy your body relies on. NAD⁺ and CoQ10 both play key roles in this process.
Why NAD⁺ matters with age
NAD⁺ occurs naturally throughout the body, but levels decline with age – making NAD⁺ metabolism an important area of healthy ageing research.
Our clinical trial
Cellular energy & wellbeing pilot study
METHODOLOGY
This study comprised of 18 healthy adults aged 35-65 who took Thrive⁺ daily. NAD⁺, CoQ10 and a range of cardiovascular, physical, blood and mental wellbeing measures were assessed at baseline and again after 30 days.
The independent study was open-label and single-arm, with no placebo group; each participant was compared with their own baseline.
THE RESULTS
1. NAD⁺ increased by 49%
After 30 days, whole-blood NAD⁺ increased from 14.04 to 20.92 µg/mL – a statistically significant rise in a key molecule involved in cellular energy production.
2. CoQ10 increased by 57%
After 30 days, plasma CoQ10 increased from 5.14 to 8.06 µg/mL – also a statistically significant rise in a key compound involved in mitochondrial energy production.
3. Thrive⁺ wasn’t just increasing NAD⁺ – the body was processing it
Researchers also measured 1-Methyl Nicotinamide (MNA), produced when NAD⁺ is metabolised.
MNA increased by 120% over the 30 days which suggests NAD⁺ pathways were actively processing within the body.
4. Significant improvements in mental wellbeing
Two validated clinical questionnaires showed statistically significant improvements in how participants felt.
The GHQ-12, a recognised measure of psychological wellbeing, improved by 10%, including:
- +31% confidence
- +23% improvement in low mood
- +19% concentration
The Profile of Mood States (POMS) also improved significantly, including:
- 32% less confusion
- 17% greater vigour
Taken together, these results show measurable changes in key cellular energy markers alongside improvements in mental wellbeing after just 30 days of Thrive⁺.
3rd party quality control
Tested for optimal safety
What to expect
Thrive⁺ shows measurable cellular changes in 30 days, but it’s designed for long-term use to support cellular energy and vitality.
24 HOURS
Your cells begin producing more NAD⁺ from NR, supporting the cellular processes involved in energy production.
BY DAY 30
After 30 days of Thrive⁺, whole-blood NAD⁺ increased by 49% and CoQ10 by 57% in our pilot study.
BY DAY 45
Clinical research around this point suggests higher NAD⁺ availability may support changes in body composition, including lean muscle.
BY DAY 180
Sustained increases in NAD⁺ may support everyday energy and endurance. In one 2020 study, participants improved their 6-minute walking distance by 17.6 metres.
AFTER 365 DAYS
With continued use, the aim is to consistently support your NAD⁺ pathway and the cellular processes associated with long-term healthy ageing.
Interactions
If you take blood thinners or antiplatelet medication such as warfarin, clopidogrel or aspirin, speak to your doctor or pharmacist before using Thrive⁺, as trans-resveratrol and CoQ10 may affect bleeding or warfarin activity.
Caution is also sensible if you take blood-pressure medication, and high dose zinc supplements can reduce copper absorption.
If you’re pregnant, breastfeeding, taking prescription medication or have a medical condition, check with a healthcare professional before use.
